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November 8, 2022

CAAT Updates

MPS World Summit Abstract Submissions and Travel Awards Open

Abstract submissions are now open for the second MPS World Summit. The deadline to submit an abstract is Tuesday, January 31, 2023. To submit an abstract, please visit the Abstract Submission page here.

Travel award submissions are also open, and we are currently accepting submissions. For more information on deadlines and required documents, please visit the Awards page here.

Frontiers in Artificial Intelligence celebrates 4th anniversary!

Last week marked the fourth anniversary since the launch of Frontiers in Artificial Intelligence. CAAT's Director, Thomas Hartung, serves as the Field Chief Editor alongside the journal's Specialty Chief Officers, editorial board, and collaborators.

Congratulations to the journal, and cheers to many more prosperous years!


Thomas Hartung and Lena Smirnova will be presenting at the upcoming ESTIV 2022 Congress in Barcelona.
  • Dr. Smirnova will present on Monday, November 21 on the topic "iPSC-derived Brain Organoids as versatile research tool for Developmental Neurotoxicity and Neurological disorders".
  • Dr. Hartung will present on Tuesday, November 22 on the topic "The key role of computational toxicology for Toxicology for the 21st Century 2.0".
To view the scientific program and learn more about the congress, please visit their website here.

NOW HIRING: Postdoctoral Fellow (In vitro) (Full-time)
Fields: in vitro neurotoxicology, metal mixtures exposures, metabolomics, transcriptomics, epigenetics

The NEMEX (Neurotoxicity due to Environmental complex Metal Mixtures Exposure) multi-investigator group is currently looking for a neuroscientist or (neuro)toxicologist who is interested in elucidating the mechanisms by which metal mixtures act in concert to elicit neurodegenerative Alzheimer's Disease-related effects.

The research is focused on the neurotoxicological effects and neurocognitive defects of metal mixtures during brain development along with gene-by-environment studies leveraging human brain organoids to discover the adverse outcome pathways (AOPs) which will help in cumulative risk assessment for Alzheimer's Disease. 

Candidates with strong backgrounds in neurotoxicology, neuroscience, and/or in vitro electrophysiology, using in vitro cell-based and/or organoid models, are encouraged to apply.

Applicants should be highly motivated, enthusiastic individuals, and have or are expected to obtain a PhD shortly in a related area. Candidates will be expected to work collaboratively with other members of the group, but must be able to design and execute experiments independently. Strong organizational and oral/written communication skills are desirable.

If interested, please submit your CV including publications, and contact information for 2-3 references to Dr. Sillé by e-mail. Please include a letter of motivation/experience with a short description of your research interests, long-term goals, and possible start dates.

The Johns Hopkins University is an Affirmative Action/Equal Opportunity Employer and encourages applications from underrepresented groups.
CALL FOR PROPOSALS: CAAT’s 2022 Reduction Award and Humane Education Award

Photo by Jo-Anne McArthur/ NEAVS / We Animals Media

For more information on these awards, please visit the Reduction & Humane Education Awards website here.

APPLICATIONS OPEN: Next Generation Humane Science Awards

Application Period NOW OPEN: Complete Applications Due by 11:59 PM EST on Sunday, January 31, 2023

The Next Generation Humane Science Award is available annually to young scientists to acknowledge and encouraging researchers who focus on replacing the use of animals in experiments. The 2023 award will be a 1st prize of $5,000 to recognize the outstanding work of one young scientist. Depending on the amount and quality of the applications, a 2nd place $4,000 award may be issued as well. Please email your completed application to

Qualification Criteria
The work must be focused on the replacement of animals used in experimentation. Excellence of research outcome as demonstrated by publications and presentations at scientific meetings. The review committee will also take into account:
  • The significance of the potential to replace animal experiments in the future.
  • Providing an inspiration to others (fellow students, members of the research group) and outreach to wider audiences.
  • The potential for the replacement methodologies to be used in a regulatory context.
2023 Eligibility Criteria
  • The candidate must be a citizen or permanent resident of the United States working at a US-based institution.
  • The candidate should not have received a PhD or similar degree earlier than 2013.
  • Current and former employees (or their family members) of the Center of Alternatives to Animal Testing at Johns Hopkins University cannot apply.
  • Application procedure and documentation
Full Application here.
  • CV: maximum two pages
  • List of all publications
  • Two reference letters, not to exceed two pages each, stating why you should receive this award. These letters should be from individuals well-qualified in the field, at least one of whom is not associated with the research itself (such as current supervisors or co-authors of publications).

CAAT in the News

Paul Locke cited in Nature article "US agency seeks to phase out animal testing"

A recent article published in nature, regarding the FDA's efforts to phase out animal testing, features Paul Locke, an environmental-health scientist and lawyer at Johns Hopkins University, who specializes in alternatives to animal testing. Locke speaks to how alternatives to animal testing are more relevant to humans, as well as the concerns around funding these methods.

Check out the full article here!


HAPPENING TOMORROW: TOXstreams Season 2: Animal-free cell culture with bio-techne

Altertox's TOXstreams has returned for a new season, which will kick off Wednesday, November 9 at 2:00 PM EST/8:00 PM CET. Dr. Jeffrey Bajramovic (Head of the 3Rs Centre at the University of Utrecht), Dr. Carol Treasure (founder of XCellR8), Dr. Yas Heidari (bio-techne European product manager) and Matteo Piumatti (Altertox) will discuss the challenges and importance of going animal-free in cell culture.

To attend this virtual event, please visit the event page here.

SAVE THE DATE: Human In, Human Out: Using Primary and Population Data for PBPK Analyses

The Physicians Committee for Responsible Medicine's is hosting their next NURA* event on Thursday, November 10 & Thursday, November 17 from 10:00 AM EST-1:00 PM EST. In this two-part NURA series, scientists and regulatory experts will present their application of PBPK models within a regulatory context, followed by an interactive discussion.

To view the agenda and register for this virtual event, please visit the event page here.

*New Approach Methodology (NAM) Use for Regulatory Application (NURA)

Upcoming Events

TOXstreams: Animal-free cell culture
November 9, 2022
Virtual Event

Lush Prize 2022 Conference
November 9-10, 2022
Virtual Event

Human In, Human Out: Using Primary and Population Data for PBPK Analyses
November 10 & November 17, 2022
Virtual Event

European Partnership for Alternative Approaches to Animal Testing
November 15, 2022
Brussels, Belgium

The FRAME Annual Lecture 2022
November 16, 2022
London, England

Latin American Congress for Alternative Methods to the Use of Animals in Teaching, Research, and Industry
November 16-18, 2022
Mexico City, Mexico

21st International Congress of the European Society of Toxicology In Vitro (ESTIV 2022)
November 21-25, 2022
Barcelona, Spain

ASPIS Open Symposium 2022
November 24-25, 2022
Barcelona, Spain

JRC Summer School on Non-animal Approaches in Science
May 23-26, 2023
Ispra, Italy

MPS World Summit
June 26-30, 2023
Berlin, Germany

WC12 Canada
August 27-31, 2023
Niagra Falls, Canada
Copyright © 2022 Johns Hopkins Center for Alternatives to Animal Testing, All rights reserved.

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