Updates from the Center for Alternatives to Animal Testing (CAAT)
December 3, 2021

News and Updates from CAAT


Join us for our second MPS World Summit Virtual Pre-Conference

MPS  World Summit: Systems Engineering of Microphysiological Systems
Virtual event - December 9th 2021, 9 am – 1 pm EST
ZOOM registration
9:00 am - 9:05 am Welcome, Thomas Hartung, JHU
9:05 am – 9:35 am Keynote: Donald Ingber, Wyss Institute, Harvard University
Human Organ Chips as Tools for Therapeutic Discovery and Clinical Mimicry
9:35 am – 10:55 am MPS Hardware and enabling Technologies (15 min talk, 5 min Q&A)
*Young investigator award nominee
9:35am-9:55am Melissa Mendoza, Binghamton University, USA
Early and Late Calcific Aortic Valve Disease-on-a-chip
9:55am-10:15am Christopher W. McAleer, Hesperos, Inc. USA
Multi-Organ System for the Evaluation of efficacy and off-target toxicity of Anti-Cancer Therapeutics
10:15am-10:35am James Tronolone*, Texas A&M University, USA
A machine-learned microvasculature optimizes physiological insulin secretion in a vascularized pancreas-chip
10:35am-10:55am Kenta Shinha*, Tokai University, Japan
Microphysiological system (MPS) platforms with high operability and pumping capability for commercialization
10:55 am – 11 am Break
11 am – 12:20 pm Cell models and applications for MPS (15 min talk, 5 min Q&A)
*Young investigator award nominee
11:00am-11:20am Devin Mair*, Johns Hopkins University, USA
Microgravity-Induced Mitochondrial Dysfunction in Human iPSC-Based 3D Cardiac Microphysiological System
11:20am-11:40am Zhong (Alan) Li*, University of Pittsburgh, USA
Synovial Joint-on-a-chip System for Modeling Osteoarthritic Features and Predicting Drug Efficacy
11:40am-12:00pm Sacha Spelier, MIMETAS, The Netherlands
Modelling T Cell-Vasculature co-culture in a high-throughput microfluidic platform
12:00pm-12:20pm Colette Bichsel, Roche, Switzerland
Engineering the neurovascular unit in vitro to improve drug delivery to the brain
12:20 pm – 12:25 pm Voting for the best presentation by young investigator
12:25 pm – 12:55 pm Panel discussion and Q&A
Panel participants:
Adrian Roth, Roche - moderator
Linda Griffith, MIT
Alysson Moutri, University of California San Diego
Peter Loskill, Tuebingen University
Uwe Marx, TissUse,
Yasuyuki Sakai, University of Tokyo
12:55 pm – 1 pm Young Investigator Travel Award Announcement, closing remarks

Registration is open! Click here to register.

Best Wishes,

The CAAT Team


hand holding centrifuge tubes

Upcoming Events

The principles of the 3Rs: Lessons Learned from History.
Talk by Anne van Veen, PhD, Radboud University

December 7, 2021
7 pm CET

MPS World Summit Virtual Conference
Systems Engineering of Microphysiological Systems
December 9, 2021

Altertox: Skin Sensitization
March 10-11, 2022
Hamburg, Germany

Altertox: Novel In vitro Methods and AOP Approaches in Genetic Toxicology
May 19-20, 2022
Oegstgeest, The Netherlands

Microphysiological Systems World Summit
May 30-June 3, 2022
New Orleans

June 13-14, 2022
Nice, France 

ICT 2022
September 18-22, 2022
Maastricht, The Netherlands

Altertox: In vitro Lung Models
November 3-4, 2022
Geneva, Switzerland

21st International Congress of the European Society of Toxicology In Vitro (ESTIV2020)
November 21-25, 2022

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