Updates from the Center for Alternatives to Animal Testing (CAAT)
Special Announcement



May 30th - June 3rd 2022
 Hilton New Orleans Riverside, New Orleans, USA

Abstract Submission Deadline: January 31st, 2022, 11:59pm PST

Microphysiological System (MPS): cell culture systems replicating (patho-) physiology through engineered organ architecture and functionality. This includes especially 3D-(co-)cultures such as organoids, organ-on-chip models, and multi-organ models, as well as the technologies to engineer and analyze these systems.
Abstracts are invited on the topic of new developments in MPS and applications of MPS. Describe your newest developments: break-throughs, advantages, challenges and the field of applications.
Top scored abstracts will be selected for an oral presentation at one of 14 scientific sessions.
Abstract submission guidelines:
All abstracts will be evaluated and selected for oral or poster presentation by the MPS Scientific Advisory Committee
Abstracts must be in English and no more than 300 words (title, authors and references excluded)
Pictures, figures, attachments are not permitted
Include no more than three references
Please submit abstract following the link:
Make sure to select the top two sessions you abstract fits the best
Maximum two abstracts are allowed for one presenting author.
All presenters must be registered for the conference, if accepted
Register for the meeting here:

New approaches in bioengineering of MPS devices
New cellular models (from bio-printing to organoids, etc.)
Individual organ MPS
Immune function and vascularization in MPS
Quality assurance of MPS
Reproducibility and Robustness
Standardization and harmonization, Validation
Road toward regulatory acceptance
MPS for disease modeling and drug efficacy testing
MPS for toxicity testing, predictive toxicology, MPS for AOP
Case studies using MPS
Pharmacokinetics and -dynamics in MPS
Computational modeling and A.I. in dialog with MPS
Precision medicine and clinical trials on chip planning
Ethical aspects of using MPS
Data collection, storage, management, dissemination

Address your questions to:
Platinum Sponsor


Gold Sponsor

Silver Sponsors

Bronze Sponsors




Contact Camila Januario ( for sponsorship and exhibitors opportunities.

New paper published about the forced swim test in rats

Kathrin Herrmann, CAAT’s Beyond Classical Refinement Director, just published a paper with colleagues Carvalho, Marques & Knight asking is it Time to Abolish the Forced Swim Test in Rats for Depression Research? The forced swim test (FST) is a controversial rodent test that has been used for decades, mainly in depression studies. The severity of the procedure makes it ethically questionable and its validity has also been questioned. In this paper we contribute new data to this debate. Available at:
3Rs Training Webinar series 2021: all webinars now on YouTube
Out of the seven 3Rs Training webinars we organized this year, four are in English and three are in German – one being a talk by CAAT Director Thomas Hartung. They are now available on YouTube. They include a talk on Human-relevant Airways Models for Disease Research by Lindsay Marshall, PhD, HSUS/HSI/Biomed21; a talk about Norecopa: a National Consensus Platform working to advance the 3Rs internationally by Prof. Adrian Smith, Norecopa; Talk by Laure-Alix Clerbaux, PhD, Joint Research Centre of the European Commission about Depicting the pathogenesis of COVID-19 using the Adverse Outcome Pathway; and a talk about The Principles of the 3Rs: Lessons Learned from History by Anne van Veen, PhD, Radboud University, Nijmegen, The Netherlands. We will continue our 3Rs Training series in February with another talk in English. Details will be announced via the CAAT Newsletter.

The European Coalition to End Animal Experiments (ECEAE) is happy to announce for the first time a unique Prize for Animal-Free Antibodies. The prize amounts to € 10,000 will be awarded for an ongoing or completed project with a focus on the development or application of animal-free antibodies. Applications can be submitted until January 15, 2022.

You can find detailed information at 

The International Foundation for Ethical Research (IFER) is now accepting pre-proposal applications for 2022-2023 Graduate Fellowships.
Applications are due no later than 11:59 PM CST on Saturday, April 30, 2022.

IFER Graduate Fellowships are one-year grants for projects that support the development, acceptance and implementation of innovative scientific methodologies that advance science and refine, reduce or replace the use of animals in research, testing or education. Grants of $12,500 are typically awarded and are renewable annually for up to three years, depending on student progress and availability of funds.
IFER recognizes the value in directing financial resources away from animal models and toward the development of human-relevant, non-animal models, as such resources pay higher dividends for human health when used for human-relevant research.
Opportunities to move away from animal models exist now more than ever with the availability of human cell lines, stem cells and tissues, computational models and researchers eager to accept the challenges of developing more human-focused methodologies. Therefore, special consideration will be given to proposals that are likely to replace the use of animals in research.
Recipients of IFER Graduate Fellowships, selected by IFER’s Scientific Advisory Board, have the potential to positively change the course of science by working to promote the advancement of more human-relevant methodologies that can also spare animal suffering. Since 1985, grants totaling more than $1 million have been awarded to promising young researchers who are developing alternatives to the use of animals in science.

Video testimonials of recent IFER Graduate Fellowship recipients can be viewed at

More information on the IFER Graduate Fellowship program, including eligibility requirements, submission guidelines, and a link to the online application can be found on the IFER website at
Questions regarding the grant application process should be directed to
Best Wishes,

The CAAT Team


hand holding centrifuge tubes

Upcoming Events

Microphysiological Systems World Summit
January 31st, 2022
Deadline for Abstracts 

Altertox: Skin Sensitization
March 10-11, 2022
Hamburg, Germany

Altertox: Novel In vitro Methods and AOP Approaches in Genetic Toxicology
May 19-20, 2022
Oegstgeest, The Netherlands

Microphysiological Systems World Summit
May 30-June 3, 2022
New Orleans

June 13-14, 2022
Nice, France 

ICT 2022
September 18-22, 2022
Maastricht, The Netherlands

Altertox: In vitro Lung Models
November 3-4, 2022
Geneva, Switzerland

21st International Congress of the European Society of Toxicology In Vitro (ESTIV2020)
November 21-25, 2022

Copyright © 2022 Johns Hopkins Center for Alternatives to Animal Testing, All rights reserved.

US Office: 615 N. Wolfe St. W7032 • Baltimore, MD 21205
Phone: 410-614-4990 • Fax: 410-614-2871

European Office: University of Konstanz
POB 600 78457 Konstanz, Germany
Phone: +49-531-882233 • Fax: +49-7531-884156