Grab your coffee and check out ten of the most interesting and instructive small molecule case studies that appeared in the literature in Oct. 2022 below:

Learn more about the molecules in the full reviews linked above which cover: why the molecules matter, how they were discovered, the key steps behind optimization, how the drugs work, why the targets were chosen, interesting toxicology and clinical data, and more.

Meet the Founder and CEO of a Billion-Dollar CDMO, Oliver Ju

​December 1st, 7pm EST

Everyone in pharma relies on contract R&D to bring compounds to the clinic. But who's behind these critical enterprises, and what are their stories? In this upcoming Drug Hunter Flash Talk, we have an exclusive interview with the founder and CEO of a CDMO doing $600M in annual revenue, Porton Pharma Solutions Ltd. He'll tell us about his story, how and why he started Porton, and what he wishes people knew about the industry.

1. Are Drugs Becoming More Lipophilic Over Time?
2. Small Molecule PI3K Inhibition in Oncology (p)
3. Landscape of AI/ML-Assisted SM Drug Discovery (Part III) (p)
4. SM from AI/ML Companies Entering the Clinic (Part II) (p)
5. AI and ML in Drug Discovery (Part I)
6. How Does This Thing Get in the Brain??
7. Synthetic Access to Stable Atropisomers in Drug Discovery
8. Molecules of the Month – September 2022
9. Molecules of the Month Runners-Up – August 2022 (p)
10. New FDA Approval: Deucravacitinib (Sotyktu) (p)
11. Voxelotor, A $5.4 Billion Reversible Covalent Aldehyde (p)
12. Computational Partnership in Small Molecule Drug Discovery