Join List
Molecules of the Month
together with

Grab your coffee and check out ten of the most interesting and instructive small molecule case studies that appeared in the literature in Oct. 2022 below:

  1. sebetralstat - an oral, on-demand plasma kallikrein (PKa) inhibitor
  2. GDC-2394 - an oral NLRP3 inflammasome inhibitor 
  3. compound 5g - a selective CDK2 kinase inhibitor 
  4. AZD1656 - an oral glucokinase activator 
  5. JNJ-64264681 - a covalent Bruton’s tyrosine kinase inhibitor 
  6. BI-0474 - a covalent KRASG12C inhibitor
  7. compound 57 - an oral allosteric EGFRL858R inhibitor
  8. AN15368 - an oral Cleavage And Polyadenylation Specificity Factor (CAPSF) inhibitor
  9. UCB7362 - an oral plasmepsin X inhibitor 
  10. BAY-069 - a branched-chain amino acid transaminase (BCAT) 1/2 inhibitor 

Learn more about the molecules in the full reviews linked above which cover: why the molecules matter, how they were discovered, the key steps behind optimization, how the drugs work, why the targets were chosen, interesting toxicology and clinical data, and more.

drug hunter flash talk
together with

Meet the Founder and CEO of a Billion-Dollar CDMO, Oliver Ju

​December 1st, 7pm EST

Everyone in pharma relies on contract R&D to bring compounds to the clinic. But who's behind these critical enterprises, and what are their stories? In this upcoming Drug Hunter Flash Talk, we have an exclusive interview with the founder and CEO of a CDMO doing $600M in annual revenue, Porton Pharma Solutions Ltd. He'll tell us about his story, how and why he started Porton, and what he wishes people knew about the industry.

more recent content
Here's a recap of other stories recently published on Drug Hunter:
  1. Are Drugs Becoming More Lipophilic Over Time?
  2. Small Molecule PI3K Inhibition in Oncology (p)
  3. Landscape of AI/ML-Assisted SM Drug Discovery (Part III) (p)
  4. SM from AI/ML Companies Entering the Clinic (Part II) (p)
  5. AI and ML in Drug Discovery (Part I)
  6. How Does This Thing Get in the Brain??
  7. Synthetic Access to Stable Atropisomers in Drug Discovery
  8. Molecules of the Month – September 2022
  9. Molecules of the Month Runners-Up – August 2022 (p)
  10. New FDA Approval: Deucravacitinib (Sotyktu) (p)
  11. Voxelotor, A $5.4 Billion Reversible Covalent Aldehyde (p)
  12. Computational Partnership in Small Molecule Drug Discovery
Get access to Premium for your team at a group rate by contacting us.
share Drug Hunter
Know drug hunters that would find this newsletter helpful? Give them your unique referral link (below) to let them sign up too.

You'll get:

  • a bonus Premium infographic or article after 1 referral
  • a free Premium slide deck after 3 referrals
  • a free month of Premium access after 10 referrals
  • and raffle entries for more fun things to top referrers, stay tuned~
  • twitterlinkedinemail
    PS: You have referred <<RH_TOTREF>> people so far
    discover together
    Copyright © 2022 Drug Hunter Inc., All rights reserved.
    You can change how often you receive messages by updating your preferences or remove yourself from this list. Having trouble? Contact us directly.