Widely used herbicides cause resistance to antibiotics, study finds
Scientists discover that Roundup and other widely used herbicides cause resistance to medically important antibiotics
Monday 30th March
A team of researchers from universities in New Zealand and Mexico have discovered that three herbicides (weed killers) widely used in agriculture and in gardens can make disease causing bacteria resistant to antibiotics.
The three herbicides they looked at were glyphosate (Roundup), the worldâ€™s most widely used pesticide, dicamba (Kamba) and 2,4-D. These were tested on E. coli and Salmonella bacteria treated with one of five different antibiotics. E.coli cause more infections that any other type of bacteria.
In most cases even low levels of the herbicides had the effect of inducing antibiotic resistance before the antibiotics had time to kill the bacteria; in a few antibiotic/herbicide combinations they actually made the bacteria more susceptible to the antibiotic, while in other cases they had no impact.
Residues of these herbicides typically found in food were not sufficient to induce resistance, but the researchers have identified a number of situations in homes and on farms where more direct exposure to the herbicides could result in antibiotic resistance in children and pets or farm animals and pollinating insects such as honeybees which can need treating with antibiotics to cure bacterial infections.
The principal concern is that doctors treating life-threatening infections often need to get the dose of antibiotics right first time in order to save lives. To do that they base decisions on existing knowledge of bacterial susceptibility to antibiotics, but where the bacteria are simultaneously exposed to antibiotics and one of the herbicides treating according to existing guidelines will frequently be unsuccessful.
Richard Young, SFT Policy Director commented, "This is a very important scientific discovery. The study shows that the use of herbicides in intensive farming may be one of the reasons that antibiotic resistance has been increasing so rapidly in recent years. We will be calling on UK and EU regulators to consider this research carefully and to reassess the safety of all herbicides to include their impact on antibiotic resistance.
In the US there are an estimated 2 million new antibiotic-resistant infections every day and it has to be noted that glyphosate is used extremely widely in the US on genetically engineered Roundup Ready crops of soya, maize and oilseed rape. It has even been found in rainwater."
Due to the development of superweeds in the US that have become resistant to Roundup, two new generations of GM crops have been developed, one of which is also resistant to 2,4-D and Roundup, the other to dicamba and Roundup. As a result the use of these herbicides is expected to greatly increase in the coming years.