Scientific Newsletter: Pain Management Issue 
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Articaine. The Best Choice of Local Anesthetic in Contemporary Dentistry.

By:  Nizharadze N, Mamaladze M, Chipashvili N, Vadachkoria D.

Dental Office Medical Emergencies

Local anesthesia forms the foundation of pain control techniques in clinical dentistry. Within the rich local anesthetic drugs available in dentistry for the prevention and management of pain 4% articaine solutions achieve highest level of anesthetic potency and lowest systemic toxicity in all clinical situations, prior to its superlative physicochemical characteristics and the pharmacological profile. 

Efficacy and Safety of Articaine Versus Lidocaine for Irreversible Pulpitis Treatment: A Systematic Review and Meta-analysis of Randomised Controlled Trials.

By: Su N, Li C, Wang H, Shen J, Liu W, Kou L


The aim of this systemic review and meta-analysis was to assess the efficacy and safety of articaine compared with lidocaine for irreversible pulpitis treatment. Databases were explored electronically and relevant journals as well as the references of the included studies were hand-searched for randomised clinical trials comparing the efficacy and safety of articaine with lidocaine in treatment of irreversible pulpits.

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