Research platform on antibiotic resistance spread through wastewater treatment plants

Newsletter # 3
March 2021                                                       

Dear Colleagues,

we are pleased to present you the third newsletter of REPARES. As in the previous issues, we introduce some of our team members and some of our activities – two expert visits to UCT, Fall school on transferable skills, and the seminar on MALDI-TOF organized by Sabina Purkrtova.

Like everybody, we struggle to keep our project running despite the COVID-19 safety measures. But, thanks to all those internet-based possibilities these days – video meetings, social media, etc. – we manage to remain active. Moreover, some of the events such as the video lectures of Celia Manaia and Roel Meulepas or Sabina’s seminar were extremely interesting and highly attended. Hopefully, you will be interested to see the news about some of these events.

We wish you inspiring reading and good nerves in the difficult COVID times.

Jan Bartacek

Principal Investigator of REPARES
University of Chemistry and Technology Prague

REPARES YouTube video
"Bacteria on a trip"

News in ARG research
World Anti-Microbial Resistance congress 2021 (November 8-9, Washington DC, United States) - The world's largest AMR conference for all stakeholders combatting Anti-Microbial Resistance

An e-exchange (e-mobility) of MSc student Stella Christou was established between TU Delft and Warsaw University (under current corona circumstances) on the database construction and bioinformatics of xenogenetic elements. On her MSc thesis, Stella is jointly supervised by David Weissbrodt and David Calderon Franco from TU Delft and by Lukasz Dziewit from Warsaw University.

Targeted metagenomics reveals inferior resilience of farm soil resistome compared to soil microbiome after manure application: Macedo, G., van Veelen, H.P.P., Hernandez-Leal, L., van der Maas, P., Heederik, D., Mevius, D., Bossers, A., Schmitt, H. (Science of The Total Environment, Volume 770, May 2021) (contribution of REPARES members)
High prevalence of antibiotic resistance in commensal Escherichia coli from healthy human sources in community settings: Nji, E., Kazibwe, J., Hambridge, T., Joko, C.A., Aboagyewa Larbi, A., Okyerewaa Damptey, L.A., Nkansa-Gyamfi, N.A:, Stålsby Lundborg, C., Quynh Lien, L.T. (Scientific Reports, Volume 11, February 2021)
Urban wastewater as a conduit for pathogenic Gram-positive bacteria and genes encoding resistance to beta-lactams and glycopeptides: Makowska, N., Bresa K., Koczura, R., Philips, A., Nowis, K., Mokracka, J. (Science of The Total Environment, Volume 765, April 2021)
Metagenomic exploration of antibiotic resistome in treated wastewater effluents and their receiving water: Raza, S., Jo, H., Kim, J., Shin, H., Hur, H.G., Unno, T. (Science of The Total Environment, Volume 765, April 2021)
Dana Vejmelkova (UCT Prague)
Dana Vejmelkova is an Assistant professor at the Department of Water Technology and Environmental Engineering of UCT Prague. Her research focuses on antimicrobial resistance at wastewater treatment plants ...
Mark Van Loosdrecht (TU Delft)
Mark has studied Environmental Engineering at Wageningen University. The broad multidisciplinary education forms a good basis for a career in fields as environmental engineering. After his Ph.D. in 1988 at the same university, he became a faculty member at the Department of Biotechnology in Delft ...
Joana Abreu Silva (UCP)
Joana Silva is a Ph.D. candidate in Biotechnology at Universidade Católica Portuguesa in collaboration with the Department of Open Innovation & Partnerships, bioMérieux France, under 4-year FCT-funded studentships (since 2020)...
Caitlin Margaret Singleton (AAU)
Caitlin Singleton’s research interest is the microbial ecology of environmental systems, particularly the microorganisms involved in bioremediation, waste reduction, and biogeochemical cycling. She is currently a postdoc in Per Halkjær Nielsen’s lab at the Center for Microbial Communities ...
Roel Meulepas (Wetsus)
Dr. ir. Roel Meulepas is an environmental engineer specialized in anaerobic environmental biotechnology and industrial wastewater treatment. Roel has over 10 years of experience in setting-up cooperative research projects ...
Adrian Gorecki (UW)
Adrian is a Ph.D. student in the Department of Environmental Microbiology and Biotechnology at UW. His doctoral thesis concern antibiotic metabolism in anthropogenically shaped and pristine microbiocenoses.... 
Meetings & Research visits

Fall school on transferable skills

was held on November 24-26, 2020. It had three parts: presentation and communication skills, creative publishing, and social media ...

Read more

Seminar on ARB detection methods

was organized by Sabina Purkrtová from UCT Prague online on January 25-27, 2021. The first day, seminar focused on the phenotyping ...

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Expert visit - Wetsus

taking place online, on December 11, 2020, and focused on Fostering cooperation with a non-academic sector. During lecture and a workshop ...

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Expert visit - UCP 

The expert visit from UCP was performed and led by prof. Célia Manaia as the leading researcher on November 18, 2020...

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REPARES Future plans & actions
  • On April 16, 2021, REPARES Seminar 2 on "Crossroads of antimicrobial resistance: environment, animal and humans" organized by UCP will take place online. Registration here
  • In the last week of April (exact dates not yet available), the second half of REPARES Fall (Spring) school will be organized. This time, we will focus on career management, negotiation skills, and grant application and research proposal writing skills. 
  • Bukola ‘Lois’ Ojobe, a 3rd Ph.D. student at UCT Prague working on removing pollutants in greywater, will be moving to Wetsus for a six-month internship working with Sam Rutten, a 2nd year Ph.D. student, and Veerle Levering, a masters student focusing on the effective use of nanofiltration for greywater recycling. 
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